2017 CPIP-D Case 4: Immunology - Detecting Latent Mycobacterium tuberculosis Infection Using Interferon-Gamma Release Assays

Learn how new methods shift TB testing from the clinic to the lab.

Credit Type: CME, SAM, CPD
Duration: 1 hour 15 minutes
Launch Date: April 17, 2017
Expiration Date: April 16, 2020 12:00 AM (ET)
Pricing: N/A
MOC Category: Medical Knowledge, Patient Care

For years there has been one method for screening individuals for latent TB infection: the tuberculin skin test (TST), which is known to have poor specificity and often results in false-positives. Several studies show interferon-gamma release assays (IGRA’s) to have a greater sensitivity and specificity than the TST. IGRAs are the preferred initial tests when screening for TB as indicated in most populations. Pathologists and residents taking this course will learn how new methods are shifting TB testing from the clinic to the lab.

After completing this SAM eligible activity and post-test, you should be able to:

  1. State the epidemiology of Mycobacterium tuberculosis (TB) infection and indications for screening, including identifying which individuals should be screened for TB.
  2. Discuss the advantages and disadvantages of interferon-gamma releasing assays (IGRAs) compared to the tuberculin skin test (TST).
  3. Describe how IGRA results should be interpreted and recommendations for follow up testing.
  4. Distinguish tests for screening for TB exposure (latent TB) to those used for diagnosis of active TB infection.

Related Link
Clinical Pathology Improvement Program

CME Information
Accreditation: The College of American Pathologists (CAP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CME Category 1: The College of American Pathologists designates this internet enduring material educational activity for a maximum of 1.25 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This activity meets the American Board of Pathology’s (ABP) Maintenance of Certification (MOC) requirements for Self-Assessment Modules (SAMs).

Continuing Professional Development (CPD), Section 3 Credit
Accreditation in Canada: This event is an Accredited Self Assessment Program (Section 3) as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada, approved by the Canadian Association of Pathologists - Association Canadienne des Pathologistes. You may claim a maximum of 1.25 hours equivalent to 3.75 credits.

Passing Requirements
You have a total of three opportunities to take and pass the post-test. If you correctly answer 70% or more of the post-test items, you may claim credit. CME/SAM credit can be applied to the American Board of Pathology (ABP) Self-Assessment Module (SAM) requirements. The AMA requires that you pass the post-test in an enduring program to claim credit; therefore, if you do not pass, you cannot claim credit.

Attention Canadian Participants: You have three opportunities to take and pass the post-test. If you do not pass the post-test after three attempts, you may still claim CPD credit (self-assessment program credits) for this activity. Please contact a representative of the CAP Learning Division at 800-323-4040 option 1 or education@cap.org with the name of this activity and the date completed to request a letter of participation.

Technical Requirements
Pop-up blockers must be turned off.

CAP Learning has recognized that some Veteran’s Administration, US Government, and military participants may have difficulty accessing the online assessment portion of this activity. If you experience difficulty or have any questions, please contact a representative of the CAP Learning Division at 800-323-4040 option 1 or education@cap.org.

This activity and evaluation is available April 17, 2017, and will expire on April 16, 2020, at 12:00 AM (ET). You MUST claim credit by this date and time.

Type:     Internet Activity (Enduring Material)
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